B Pharm Pharmacology 1 Notes

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Download B Pharm Pharmacology 1 Notes

Download  Pharmacology 1 Notes for b pharm 4th sem notes

This pharmacology 1 notes  will help all the B Pharmacy and D Pharmacy students very much to make a good score in their university and any other competitive exams.

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UNIT-1

1. General Pharmacology
a. Introduction to Pharmacology- Definition, historical landmarks and scope of
pharmacology, nature and source of drugs, essential drugs concept and routes of
drug administration, Agonists, antagonists( competitive and non competitive), spare
receptors, addiction, tolerance, dependence, tachyphylaxis, idiosyncrasy, allergy. b. Pharmacokinetics- Membrane transport, absorption, distribution, metabolism and
excretion of drugs .Enzyme induction, enzyme inhibition, kinetics of elimination


UNIT-2

General Pharmacology
a. Pharmacodynamics- Principles and mechanisms of drug action. Receptor theories
and classification of receptors, regulation of receptors. drug receptors interactions
signal transduction mechanisms, G-protein–coupled receptors, ion channel receptor,
transmembrane enzyme linked receptors, transmembrane JAK-STAT binding
receptor and receptors that regulate transcription factors, dose response
relationship, therapeutic index, combined effects of drugs and factors modifying
drug action.
b. Adverse drug reactions.
c. Drug interactions (pharmacokinetic and pharmacodynamic)
d. Drug discovery and clinical evaluation of new drugs -Drug discovery phase, preclinical evaluation phase, clinical trial phase, phases of clinical trials and
pharmacovigilance.


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UNIT-3

2. Pharmacology of drugs acting on peripheral nervous system
a. Organization and function of ANS. b.Neurohumoral transmission,co-transmission and classification of neurotransmitters. c. Parasympathomimetics, Parasympatholytics, Sympathomimetics, sympatholytics.
d. Neuromuscular blocking agents and skeletal muscle relaxants (peripheral).
e. Local anesthetic agents.
f. Drugs used in myasthenia gravis and glaucoma


UNIT-4

3. Pharmacology of drugs acting on central nervous system
a. Neurohumoral transmission in the C.N.S.special emphasis on importance of various
neurotransmitters like with GABA, Glutamate, Glycine, serotonin, dopamine. b. General anesthetics and pre-anesthetics. c. Sedatives, hypnotics and centrally acting muscle relaxants.
d. Anti-epileptics
e. Alcohols and disulfiram


Other Subjects Notes Given below :

  • Pharmacology 1 Click
  • Pharmacognosy and Phytochemistry 1 Click
  • Organic Chemistry 3 Click
  • Medicinal Chemistry 1 Click
  • Physical Pharmaceutics 2 Click

UNIT-5

3. Pharmacology of drugs acting on central nervous system
a. Psychopharmacological agents: Antipsychotics, antidepressants, anti-anxiety agents,
anti-manics and hallucinogens.
b. Drugs used in Parkinsons disease and Alzheimer’s disease. c. CNS stimulants and nootropics.
d. Opioid analgesics and antagonists
e. Drug addiction, drug abuse, tolerance and dependence


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