Pharmaceutical Organic Chemistry 3 Notes pdf 2022

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In this article we provide you b pharmacy 4th semester notes pdf.

pharmaceutical organic chemistry 3 notes pdf

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This Pharmaceutical Organic Chemistry Notes will help all the B Pharmacy and D Pharmacy students very much to make a good score in their university and any other competitive exams.

UNIT-1

Stereo isomerism
Optical isomerism – Optical activity, enantiomerism, diastereoisomerism, meso compounds
Elements of symmetry, chiral and achiral molecules
DL system of nomenclature of optical isomers, sequence rules, RS system of
nomenclature of optical isomers
Reactions of chiral molecules
Racemic modification and resolution of racemic mixture. Asymmetric synthesis: partial and absolute


UNIT-2

Geometrical isomerism
Nomenclature of geometrical isomers (Cis Trans, EZ, Syn Anti systems)
Methods of determination of configuration of geometrical isomers.
Conformational isomerism in Ethane, n-Butane and Cyclohexane. Stereo isomerism in biphenyl compounds (Atropisomerism) and conditions for optical
activity. Stereospecific and stereoselective reactions


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UNIT-3

Heterocyclic compounds:
Nomenclature and classification
Synthesis, reactions and medicinal uses of following compounds/derivatives
Pyrrole, Furan, and Thiophene
Relative aromaticity and reactivity of Pyrrole, Furan and Thiophene


UNIT-4

Synthesis, reactions and medicinal uses of following compounds/derivatives
Pyrazole, Imidazole, Oxazole and Thiazole.
Pyridine, Quinoline, Isoquinoline, Acridine and Indole. Basicity of pyridine
Synthesis and medicinal uses of Pyrimidine, Purine, azepines and their derivatives


Other Subjects Notes Given below :

  • Pharmacology 1 Click
  • Pharmacognosy and Phytochemistry 1 Click
  • Organic Chemistry 3 Click
  • Medicinal Chemistry 1 Click
  • Physical Pharmaceutics 2 Click

UNIT-5

Reactions of synthetic importance
Metal hydride reduction (NaBH4 and LiAlH4), Clemmensen reduction, Birch
reduction, Wolff Kishner reduction.
Oppenauer-oxidation and Dakin reaction.
Beckmanns rearrangement and Schmidt rearrangement.
Claisen-Schmidt condensation

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