Medicinal Chemistry 1 Notes pdf
Download medicinal chemistry 1 notes pdf for b pharmacy 4th semester. This medicinal chemistry notes pdf will give short overview about all the 5 units of this subject.
All the medicinal chemistry 1 notes pdf are prepared by the renowned professors from different universities of India.
In this article we will provide the b pharmacy 4th semester notes pdf.
Download Medicinal Chemistry 1 Notes pdf
Download Handwritten Medicinal Chemistry 1 Notes pdf for free .
All the b pharmacy notes pdf free download available in this website are free to download and easy to understand.
This Medicinal Chemistry 1 Notes pdf will help all the B Pharmacy and D Pharmacy students very much to make a good score in their university and any other competitive exams.
UNIT-1
Introduction to Medicinal Chemistry
History and development of medicinal chemistryPhysicochemical properties in relation to biological action
Ionization, Solubility, Partition Coefficient, Hydrogen bonding, Protein
binding, Chelation, Bioisosterism, Optical and Geometrical isomerism.
Medicinal chemistry 1 (UNIT-2)
Drugs acting on Autonomic Nervous System
Adrenergic Neurotransmitters:
Biosynthesis and catabolism of catecholamine. Adrenergic receptors (Alpha & Beta) and their distribution.
Sympathomimetic agents: SAR of Sympathomimetic agents
Direct acting: Nor-epinephrine, Epinephrine, Phenylephrine*, Dopamine
Methyldopa, Clonidine, Dobutamine, Isoproterenol, Terbutaline, Salbutamol*, Bitolterol, Naphazoline, Oxymetazoline and Xylometazoline. Indirect acting agents: Hydroxyamphetamine, Pseudoephedrine, Propylhexedrine.
Agents with mixed mechanism: Ephedrine, Metaraminol.
Adrenergic Antagonists:
Alpha adrenergic blockers: Tolazoline*, Phentolamine, Phenoxybenzamine, Prazosin, Dihydroergotamine, Methysergide.
Beta adrenergic blockers: SAR of beta blockers, Propranolol*,
Metibranolol, Atenolol, Betazolol, Bisoprolol, Esmolol, Metoprolol,
Recommended Posts
UNIT-3
Cholinergic neurotransmitters:
Biosynthesis and catabolism of acetylcholine. Cholinergic receptors (Muscarinic & Nicotinic) and their distribution.
Parasympathomimetic agents: SAR of Parasympathomimetic agents
Direct acting agents: Acetylcholine, Carbachol*, Bethanechol, Methacholine, Pilocarpine. Indirect acting/ Cholinesterase inhibitors (Reversible & Irreversible):
Physostigmine, Neostigmine*, Pyridostigmine, Edrophonium chloride, Tacrine hydrochloride, Ambenonium chloride, Isofluorphate, Echothiophate iodide, Parathione, Malathion.
Cholinesterase reactivator: Pralidoxime chloride.
Cholinergic Blocking agents: SAR of cholinolytic agents
Solanaceous alkaloids and analogues: Atropine sulphate, Hyoscyamine sulphate, Scopolamine hydrobromide, Homatropine hydrobromide, Ipratropium bromide*.
Synthetic cholinergic blocking agents: Tropicamide, Cyclopentolate hydrochloride, Clidinium bromide, Dicyclomine hydrochloride*, Glycopyrrolate, Methantheline bromide, Propantheline bromide, Benztropine mesylate, Orphenadrine citrate, Biperidine hydrochloride, Procyclidine hydrochloride*, Tridihexethyl chloride, Isopropamide iodide, Ethopropazine hydrochloride.
UNIT-4
A. Sedatives and Hypnotics:
Benzodiazepines: SAR of Benzodiazepines, Chlordiazepoxide, Diazepam*,Oxazepam, Chlorazepate, Lorazepam, Alprazolam, Zolpidem Barbiturtes: SAR of barbiturates, Barbital*, Phenobarbital, Mephobarbital, Amobarbital, Butabarbital, Pentobarbital, Secobarbital
Miscelleneous:
Amides & imides: Glutethmide. Alcohol & their carbamate derivatives: Meprobomate, Ethchlorvynol.
Aldehyde & their derivatives: Triclofos sodium, Paraldehyde. B. Antipsychotics
Phenothiazeines: SAR of Phenothiazeines – Promazine hydrochloride, Chlorpromazine hydrochloride*, Triflupromazine, Thioridazine hydrochloride, Piperacetazine hydrochloride, Prochlorperazine maleate, Trifluoperazine hydrochloride.
Ring Analogues of Phenothiazeines: Chlorprothixene, Thiothixene, Loxapine succinate, Clozapine
. Fluro buterophenones: Haloperidol, Droperidol, Risperidone. Beta amino ketones: Molindone hydrochloride. Benzamides: Sulpieride. C. Anticonvulsants: SAR of Anticonvulsants,
mechanism of anticonvulsant action Barbiturates: Phenobarbitone, Methabarbital. Hydantoins: Phenytoin*, Mephenytoin, Ethotoin Oxazolidine diones: Trimethadione, Paramethadione
Succinimides:
Phensuximide, Methsuximide, Ethosuximide* Urea and monoacylureas: Phenacemide, Carbamazepine*
Benzodiazepines: Clonazepam Miscellaneous: Primidone, Valproic acid , Gabapentin, Felbamate
Other Subjects Notes Given below :
UNIT-5
Drugs acting on Central Nervous System General anesthetics:
Inhalation anesthetics: Halothane*, Methoxyflurane, Enflurane, Sevoflurane, Isoflurane, Desflurane. Ultra short acting barbitutrates: Methohexital sodium*, Thiamylalsodium, Thiopental sodium.
Dissociative anesthetics: Ketamine hydrochloride.* Narcotic and non-narcotic analgesics Morphine and related drugs: SAR of Morphine analogues, Morphine sulphate, Codeine, Meperidine hydrochloride, Anilerdine hydrochloride, Diphenoxylate hydrochloride, Loperamide hydrochloride, Fentanyl citrate*,Methadone hydrochloride*, Propoxyphene hydrochloride, Pentazocine, Levorphanol tartarate.
Narcotic antagonists: Nalorphine hydrochloride, Levallorphan tartarate, Naloxone hydrochloride. Anti-inflammatory agents: Sodium salicylate, Aspirin, Mefenamic acid*,Meclofenamate, Indomethacin, Sulindac, Tolmetin, Zomepriac, Diclofenac, Ketorolac, Ibuprofen*, Naproxen, Piroxicam, Phenacetin, Acetaminophen, Antipyrine, Phenylbutazone
If you face any difficulty in downloading the notes then please feel free to contact us at our social network site which are given below.We will definitely fix your issue.
Follow us On
Disclaimer
The content of Pharmaedu. in is provided for information and educational purposes only. WE are not the owner of any PDF Material/Books/Notes/Articles published on this website. No claim is made as to the accuracy or authenticity of the PDF Material/Books/Notes/Articles of the website. In no event will this site or owner be liable for the accuracy of the information contained on this website or its use
Pharmaedu.in provides freely available PDF Materials/Books/Notes/Articles on the internet or other resources like Links etc. This site doesn’t take any responsibility and legal obligations due to the illegal use and abuse of any information published on the website. No responsibility is taken for any information that may appear on any linked website.
Conclusion
Here in this article ‘’Medicinal Chemistry 1 Notes pdf’’ we have provided the latest available study notes for the B Pharmacy students. If you find this helpful then don’t forget to share it with your friends. you face any difficulty downloading Notes then contact us directly at pharmaedu5@gmail.com