Physical Pharmaceutics 1 Notes pdf Free Download

In this article we provide physical pharmaceutics 1 notes pdf for b pharmacy 3rd semester students. All the study materials are very helpful for b pharm 3rd semester students.

These notes will helpful for the b pharmacy students to gain knowledge in physical pharmaceutics and score a good marks in their exams.

Sometimes students find difficulty in getting the important notes to study.So here we have prepared important handwritten notes for physical pharmaceutics 1.

Physical Pharmaceutics 1 Notes pdf Free download 2024

Physical Pharmaceutics 1 notes deals with the Study of all categories of microorganisms especially for the production of alcohol
antibiotics, vaccines, vitamins enzymes .

This Physical Pharmaceutics 1 Notes pdf Free download will help all the B. Pharmacy and D. Pharmacy students very much to make a good score in their university and any other competitive exams.

UNIT-1

Solubility of drugs:
Solubility expressions, mechanisms of solute solvent interactions, ideal solubility parameters, solvation & association, quantitative approach to the factors influencing solubility of drugs, diffusion principles in biological systems.

Solubility of gas in liquids, solubility of liquids in liquids, (Binary solutions, ideal solutions) Raoult’s law, real solutions. Partially miscible liquids, Critical solution temperature and applications. Distribution law, its limitations and applications

Physical Pharmaceutics 1 (Unit-2)

States of Matter and properties of matter: State of matter, changes in the state of matter, latent heats, vapour pressure, sublimation critical point, eutectic mixtures, gases, aerosols – inhalers, relative humidity, liquid complexes, liquid crystals, glassy states, solidcrystalline, amorphous & polymorphism.

Physicochemical properties of drug molecules: Refractive index, optical rotation, dielectric constant, dipole moment, dissociation constant, determinations and applications

UNIT-3

Surface and interfacial phenomenon: Liquid interface, surface & interfacial tensions, surface free energy, measurement of surface & interfacial tensions, spreading coefficient, adsorption at liquid interfaces, surface active agents, HLB Scale, solubilisation, detergency, adsorption at solid interface.

UNIT-4

Complexation and protein binding: Introduction, Classification of Complexation, Applications, methods of analysis, protein binding, Complexation and drug action, crystalline structures of complexes and thermodynamic treatment of stability constants.

UNIT-5

pH, buffers and Isotonic solutions: Sorensen’s pH scale, pH determination (electrometric and calorimetric), applications of buffers, buffer equation, buffer capacity, buffers in pharmaceutical and biological systems, buffered isotonic solutions.

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Conclusion

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