B Pharm 2nd Semester Biochemistry Notes pdf
Download b pharm 2nd semester biochemistry notes pdf . All the b pharm 2nd semester biochemistry notes available in this website are free to download and easy to understand.
These biochemistry notes pdf are very important for b pharm 2nd semester students. This will help B pharmacy students to get good marks in their final examination.
B pharm 2nd semester biochemistry notes pdf are prepared by renowned professors from different universities of India. All b pharm notes provided here are easy to understand and free to download.
B PHARM 2ND SEMESTER BIOCHEMISTRY NOTES
This B Pharm 2nd semester biochemistry notes pdf are prepared by renowned professors from different universities of India. They are very useful study materials for the final year B pharmacy students.
In this website we also provide all semester study materials which are very helpful for b pharmacy students. This helps them to get a good marks in their exam.
Other important b pharm study materials include b pharm practical files , b pharmacy previous year question paper , important probable questions and other necessary information regarding b pharmacy.
UNIT-1
Biomolecules Introduction, classification, chemical nature and biological role of carbohydrate, lipids, nucleic acids, amino acids and proteins.
Bioenergetics Concept of free energy, endergonic and exergonic reaction, Relationship between free energy, enthalpy and entropy; Redox potential.
Energy rich compounds; classification; biological significances of ATP and cyclic AMP
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UNIT-2
Carbohydrate metabolism Glycolysis – Pathway, energetics and significance Citric acid cycle- Pathway, energetics and significance HMP shunt and its significance; Glucose-6-Phosphate dehydrogenase (G6PD) deficiency Glycogen metabolism Pathways and glycogen storage diseases (GSD) Gluconeogenesis- Pathway and its significance Hormonal regulation of blood glucose level and Diabetes mellitus
Biological oxidation Electron transport chain (ETC) and its mechanism. Oxidative phosphorylation & its mechanism and substrate phosphorylation Inhibitors ETC and oxidative phosphorylation/Uncouplers
UNIT-3
Lipid metabolism
β-Oxidation of saturated fatty acid (Palmitic acid)
Formation and utilization of ketone bodies; ketoacidosis De novo synthesis of fatty acids (Palmitic acid) Biological significance of cholesterol and conversion of cholesterol into bile acids,
Steroid hormone and vitamin D Disorders of lipid metabolism: Hypercholesterolemia, atherosclerosis, fatty liver and obesity.
Amino acid metabolism
General reactions of amino acid metabolism: Transamination, deamination & decarboxylation, urea cycle and its disorders.
Catabolism of phenylalanine and tyrosine and their metabolic disorders (Phenyketonuria, Albinism, alkeptonuria, tyrosinemia) Synthesis and significance of biological substances; 5-HT, melatonin, dopamine, noradrenaline, adrenaline Catabolism of heme; hyperbilirubinemia and jaundice
UNIT-4
Nucleic acid metabolism and genetic information transfer
Biosynthesis of purine and pyrimidine nucleotides Catabolism of purine nucleotides and Hyperuricemia and Gout disease.
Organization of mammalian genome Structure of DNA and RNA and their functions DNA replication (semi conservative model) Transcription or RNA synthesis Genetic code, Translation or Protein synthesis and inhibitors
UNIT-5
Enzymes
Introduction, properties, nomenclature and IUB classification of enzymes Enzyme kinetics (Michaelis plot, Line Weaver Burke plot) Enzyme inhibitors with examples Regulation of enzymes:
Enzyme induction and repression, allosteric enzymes regulation Therapeutic and diagnostic applications of enzymes and isoenzymes Coenzymes –Structure and biochemical functions
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